Profile Summary

Medical Qualification: DNB (General Medicine), M.N.A.M.S, Affiliate AACR Medical Oncology & Hemato-Oncolgy (Clinical) - 23 years Medical Oncology & Hematooncology and Stem Cell Transplant - 21 years

Designation at JHRC: Consultant, Medical Oncology & Bone Marrow Transplant 

Area of expertise:

• Stem cell transplant/BMT/Chemotherqapy
• Targeted & Immunotherapy; bispecific antibodies in leukemia and myeloma
• CAR-T cell therpay
• Radioimmunotherapy in lymphoma
• Radiopeptide therapy (PRRT therapy)
• Clinical application of Mesenchymal stem cells in regenerative medicine

Introduction:

Dr Ganapathi Bhat is a Senior Consultant with the Medical Oncology and Bone Marrow Transplant department at Jaslok Hospital & Research Centre, Mumbai, India.

Dr Bhat has vast experience in Haematological malgnancies, Solid tumours management, Bone Marrow Transplant, Immunotherapy and trageted therapy. He is trained in carrying out both autologous and allogenic hematopoetic stem cell transplant for various disorders and undertake PRRT therapy for neuroendocrine tumour and metastic carcinoma of prostate.

He gained experience in Bone Marrow Transplant at Kuwait Cancer Control Centre, where he worked in Lymohoma and BMT. He underwent an advanced ICAs training course on Blood Cell Transplantation at ULM University, Germany; and ESH-EBMT training course on Haematopoetic Stem Cell Transplantation at LA-BAULE, France in 2011 and ESH-EBMT training course on Haematopoetic Stem Cell Transplantation at Alicante, Spain.

Dr Bhat is affiliated with Asian-Pacific Blood and Bone Marrow Transplantation, European Heamatology Association, European Society of Medical Oncology, American Association for Cancer Research and the College of Chest Physicians of India. In addition, he has several publications, including books, chapters to his name. Currently, he is a mentor for MSc and PhD students in Applied Biology and Fellowship in Medical Oncology (under MUHS) for Mumbai University. Dr Bhat was also part of Kuwait University Teaching Faculty for MRCP-Haematology/ Pathology during his Kuwait Cancer Control Centre tenure. 

Awards & Publications:

Awards:

• Vishist Chikitsak Medal, 1997
• Rajiv Gandhi Gold Medal Award - GEPRA, 2012
• Mother Teresa Gold Medal Award - GEPRA, 2012-2013
• Jawaharlal Nehru Gold Medal Award – GEPRA, 2013- 2014
• National Health Achievers Award, 2015 - Best Oncologist of India
• Excellent Medical Oncologist Award, 2022 - DOCTOR 365
• Iconic Healthcare Leader Award, 2022 - DYNERGIC Business Solutions

Research Experience:

• Project Title- "Isolation and Characterization of Regulatory T Cells in Heterogeneous Population" at Jaslok Hospital & Research Centre, Mumbai 400026, Maharashtra, India

  The research is carried out by isolation and characterization of the CD4+ CD25+ regulatory T cells from the peripheral blood by Flowcytometry for further in various clinical conditions like Graft versus Host Disease in post Allogenic hematopoetic stem cell transplant, various autoimmune disorders like Type I diabetes, Hashimotos Thyroiditis, rheumatoid arthritis, autoimmune haptitis, SLE; Pregnancy less than 14 weeks, and cord blood. Our aim is to have a comparative study of the population of regulatory T cells in enumerated disorders with the control samples.

• Project Title- "Prospective study of xyton versus culture in stem cell transplant and haematological paatients with suspected infection and sepsis- 100 patients"

Publications:

Abstracts-

• Incidence and prognostic significance of anemia in non-Hodgkin’s lymphoma patients. ABSTRACT SECTION [72-81, iii57]- ESMO SUMMER EDUCATIONAL CONFERENCE,EDINBURG,SCOTLAND,UK,JUNE 2003 Kamlesh.p.sajnani.,Ganapathi.bhat.SalemShemmari
• Evaluation of cyclic chemotherapy in non-Hodgkin’s lymphoma patients infected with chronic hepatitis. POSTER SESSION [ABSRACT BOOK-1016] ECCO-12 COPENHAGEN. SEPT 2003. K.Kamlesh P Sajnani, G.GanapathiBhat,I.IqbalSiddique,S.Al-Shemmari,F.Fuad Al-Ali Citation-European Cancer Conference Abstract book,Vol I No 5 Sept 2003,1016
• Primary extra nodal lymphomas: analyses of clinical characteristics a single Centre experience. POSTER SESSION [ABSTRACT BOOK 599P], ESMO 29 TH CONGRESS VIENNA. OCT –NOV 2004(Annals of Oncology supplement 3,vol 15,2004,abstract book 29th ESMO Congress) Ganapathi.M.Bhat,Salem Al-Shemmari,ReemAmeen,Kamlesh P Sajnani,JanGyarfas
• Non-Hodgkin’s lymphoma in elderly patients- a retrospective single institution analysis. POSTER SESSION.GERIATRIC ONCOLOGYCONFERENCE (SOUVENIR & ABSTRACT BOOK).OCTOBER 14-16, 2005.Tata Memorial Hospital.Mumbai.India. Ganapahi.Bhat.M.,Salem Al-Shemmari.,Kamlesh P.Sajnani.,Jan Gyarfas
• Analysis of Clinical Characteristics and Prognostic variables of Hodgkin’s Lymphoma: A single Center Experience. Abstract section, Publication Number 4647.47th ASH Annual Meeting Dec.2005, New Orleans,LA.(Citation –Blood,DEC.2005.November abstract issue). Salem Al-Shemmari., Ganapahi.Bhat.M., Kamlesh P. Sajnani.,Reem Ameen
• Clinical profile and acute adverse events in Stem Cell Transplantation: - Jaslok Hospital Experience. Poster presentation, Ganapathi.Bhat.M., Suvarna .Achrekar., AnjanaSainani., Reetu Jain., ChetnaBakshi., Akshay Shah., Sujata Vasani.,MehboobBasade.,Samir.S.Shah.,BomanN.DhabharTapanK.Saikia., S. H .Advani.Division of Medical Oncology and Bone marrow transplant Unit Jaslok Hospital and Research Centre , Mumbai; Mumbai Hematology Group Annual Conference 14-15thApril 2007,Tata Memorial Hospital, Mumbai
• Impact of CD34+cells as predictor of Hematopoietic recovery in Autologous Peripheral Blood Stem Transplant- Single center experience. Oral presentation, Suvarna.Achrekar.Ganapathi.Bhat.M., MamtaYargop,AnjanaSainani.,VPAntia,Reetu Jain.,ChetnaBakshi.,Akshay Shah.,Sujata Vasani., Tapan K.Saikia.,S. H .Advani.Division of Medical Oncology and Bone marrow transplant Unit Jaslok Hospital and Research Centre , Mumbai; Mumbai Hematology Group Annual Conference 14-15thApril 2007,Tata Memorial Hospital, Mumbai
• Stem cell transplant in diabetes –a long road ahead- 04/12/2012, 5th BIT’s WORLD conference of Regenerative Medicine and Stem Cell Research-2012, Guanzchou, China. DR.GANAPATHI.BHAT.M
• Probing Mesenchymal stem cells from lab to life: Are we poised to signal the dawn of a new frontier? DR.GANAPATHI.BHAT.M. abstract selected for oral presentation- 3 rd World Congress of Stem Cell Research and cell science 2013, Baltimore, USA. Nov.20-23,2013
• Cellular cancer therapy: A future conundrum or reality? 1stNational conference of Stem cell society of India, MUMBAI Feb-March -2014
• Ameliorating acute and chronic GVHD: Is cellular therapy emerging as a befitting alternative? RMSC- 2014 HAISAKOU CHINA, 7th BIT’s International Conference on regenerative medicine and stem cell research Nov. 2014
• Blastic Plasmacytoid Dendritic Cell Neoplasm - A Rarity, Shweta Puri, Dr. GanapathiBhat.M. International CME in Pathology (Histopathology and Cytopathology), 5th - 7th Feb, 2015, Goa. India
• The stem cell ethical impasse: How long will it take to realize their translational preparedness? - Oral presentation –Dr.Ganapathi.Bhat.M. 6th International conference on stem cells and cancer, proliferation, differentiation and apoptosis. 2-5thOctober 2015, PUNE, INDIA
• Extending expiry: Is the placenta a worthy candidate to bank on for regenerative medicine? RMSC, Korea 2016. DR.GANAPATHI.BHAT.M
• Unmasking the masquerading cancer cells: have we made progress with the revival of immunotherapy? 5thEuropean Immunology Conference, July 21-23, 2016, Berlin, Germany
• “Fighting the good fight: GVHD in allogeneic hematopoietic stem cell transplant”, 8th World Congress and Expo on Cell and Stem Cell Research, March 20-22, 2017 in Orlando, Florida, USA Dr. Ganapathi Bhat M, Ms Pooja Shahapurakar
• “Hematopoietic Stem Cell Transplantation (HSCT): A decade long Single-Tertiary Centre experience at Mumbai”, Best of Ash-2016 & 21st Annual CME in Hematology, 19th to 21st January, 2017, Mumbai Vasu Babu G, Reetu Jain, Ganapathi Bhat m. AnjanaSainani, Basade M, Samir Shah, Tapan Kumar Saikia, S. H. Advani
• Stem Cells –New Era of Regenerative Therauptics RMSC, Nov 2017, Singapore. DR.GANAPATHI.BHAT.M
• Immunotherapy in cancer: Early success dwarfed by emergent real-world challenges and scope for Ayurveda immune prevention. World Congress on Cancer, Feb 2018, Jaipur, Rajasthan, India, Ganapathi Bhat M, Govind R. Reddy, Manohar S. Gundeti
• “Defining Genetic and Molecular determinants in Allogeneic Hematopoietic Stem Cell Transplant” 21st International Symposium on Molecular Medicine, World Academy of Sciences, 12-14 April, 2018, Bangkok, Thailand Dr. Ganapathi Bhat, Pooja Shahapurkar, Dr.Rasika. Bhat
• 21. T3151 MUTATION STATUS POST HEMATOPOETIC STEM CELL

Articles:

• Association of congenital chromosomal syndromes and Hodgkin's disease. Not a mere co-incidence. Report of 2 cases. Austral Asian Journal of Cancer, Vol 5 No 2 April 2006 ISSN0972-2556 109-111. Ganapathi.Bhat.M., Salem Al-Shemmari, Kamlesh P. Sajnani, Jan Gyarfas, Bhavin Choksi
• Non-Hodgkin's Ovarian Lymphoma in an Adolscent - A New Dimension to Diagnostic Approach and Treatment Ganapathi. Bhat. M., Salem Al-Shemmari, Kamlesh P. Sajnani, Jan Gyarfas. Austral - Asian Journal of Cancer ISSN-0972-2556, Vol. 5, No. 4, October 2006
• Combined applications of fine needle aspiration cytology and flow cytometric immunophenotyping for diagnosis and classification of Non Hodgkin Lymphoma. CytoJournal 2006,3:24 doi:10.1186/1742-6413-3-24 PranabDey, Thasneem Ameer, Aisha Al Jassar, Salem Al Shemmari, Sanjay Jogai, Ganapathi Bhat M, Ayesha Al Quallaf, Zahia Al Shammari
• Side line the side effects- Contribution to Research Article for EXPRESSPHARMA ANNIVERSARY SPECIAL- 2008 DR. GANAPATHI BHAT M.
• Childhood Chronic Myeloid Leukemia. CML Newsletter. Vol.1, 2008. Dr.Ganapathi.Bhat.M
• Thinking about cancer- Helping hand 4 Cancer care, Newsletter, Vol.4 Edition 1, Jan.-June 2009 DR.Ganapathi.Bhat.M
• Pharmacogenomics- "The tailor made drugs"- Onco-sense, Newsletter, Vol-4, 2009 DR.Ganapathi.Bhat.M
• Adult mesenchymal stemm cells and its Clinical Applications- THE BIO MEDIC JOURNAL, issue no-8, 2009;18-24. Ganapathi.Bhat.M
• Prevention-PTLD, Chapter on PTLD, Newsletter, 2010, India. Ganapathi.Bhat.M
• Status of stem cell therapy in type -1 diabetics- International journal of diabetes for developing countries-July-Sept;vol 30.issue-3; 113-117 Ganapathi.Bhat.M
• Malignant amelanotic melanoma -A diagnostic surprise: Flurodeoxyglocose positron emission tomography-Computed tomography and immunohistochemistry clinch the 'final diagnosis' Prathamesh V Joshi, Vikram R Lele, Nusrat J Aland, Ganapathi Bhat, Snigdha PratapAjinkya, Roma P Patel, V Prathamesh, Joshi. Journal of cancer research and therapeutics. 09/2012; 8(3):451-453
• F-18 flourodeoxyglucose positron emission tomography/computed tomography findings in a case of hepatosplenic T-cell lymphoma. Prathamesh V Joshi, Vikram R Lele, Ganapathi M Bhat, Sonal Garg, Arun Chitale Journal of cancer research and therapeutics. 01/2012; 8(1):106-8
• Extramedullary plasmocytoma: A rare malignancy in renal transplant recipient- Keyur Dave, Madan M. Bahadur, Ganapathi M. Bhat, Samir Shah Case report - Indian journal of transplantation. 07/2015
• Primary Liver Sinusoidal Non-Hodgkin's Lymphoma Presenting as Acute Liver Failure Journal of Clinical and Experimental Hepatology (2015) – Aabha Nagral, Ajay Jhaveri, Vilesh Kalthoonical, Ganapathi Bhat M. Pravin Mahajan, Anita Borges
• Antioxidants as precision weapons in war against cancer chemotherapy induced toxicity – Exploring the armoury of obscurity, Kanchanlata Singh, Mustansir Bhori, Yasar Arfat Kasu, Ganapathi Bhat, Thankamani Marar. December 2017 Saudi Pharmaceutical Journal, DOI: 10.1016/j.jsps.2017.12.013
• Loss of Human Epidermal Growth Factor Receptor 2 (HER-2) Expression after Trastuzumab Treatment in Locally Advanced Breast Cancer: A Case Report, Ganapathi M Bhat, Vasu Babu Goli, Rajas Patel, Reetu Jain, November 2017, DOI: 10.21276/aimdr.2017.3.6.MC1, Annals of International Medical and Dental Research, Vol (3), Issue (6)
• Musculoskeletal chronic graft versus host disease – A rare complication of allogeneic hematopoietic stem cell transplantation: A case report and review of its literature, October 2017, South Asian Journal of Cancer 6(4), DOI:10.4103/sajc.sajc_145_17
• Monoclonal Gammopathy in Chronic Lymphocytic Leukaemia : A Case report and Review of its Literature, January 2017, Indian journal of medical and paediatric oncology, xx(xx), DOI: 10.4103/ijmpo.ijmpo_129_17, Vasu Babu Goli, Reetu Jain, Ganapathi M Bhat, Anjana Sainani, S H Advani
• Relapsed Plasmablastic Lymphoma in an HIV infected patient – Experience of high-dose chemotherapy with Autologous Stem Cell Rescue: A case report with Review of literature, Indian journal of medical and paediatric oncology, DOI: 10.1055/s-0042-1742455, ISSN 0971-5851, Ganapathi Bhat M., Reetu Jain, Samir S. Shah, Fahad Afzal Shaikh

Chapters:

• Bcr-abl mutations: Identification and clinical signification-Chapter-19 Hematology today-2009, Ganapathi.Bhat.M, Rasika.G.Bhat
• Radioimmunotherapy in lymphoma - chapter- Hematology today-2010, Ganapathi.Bhat.M, Rasika.G.Bhat
• CNS Lymphoma- negotiating the challenges in the management – case based chapter-Hematology today 2015. Ganapathi.Bhat.M, Rasika.G.Bhat. Aditi Chincholi 4
• From trial to Therapeutics: Are Mesenchymal Stem Cells Promising in cellular Therapy?”, Frontiers in Stem Cell and Regenerative Medicine Research, 2017 Volume 4, Chapter 5, Page 234-262. Dr. Ganapathi Bhat M, Ms Pooja Shahapurakr, Dr. Rasika G. Bhat

Memberships:

• Member of BIT's Congress-RMSC since August 2016
• Member of Asian-Pacific Blood and Bone Marrow Transplantation since 2014
• Member of European Hematology Association: Admitted as Member of European Haematology Association in April 2005. (Membership No-4010)
• Member of European Society of Medical Oncology: Admitted as Member of European Society of Medical Oncology in June 2005
• Member of American Association for Cancer Research: Admitted as an Affiliate Member in good standing of American Association for Cancer Research in July 2005 (Membership No-123632)
• Member of ISBMT
• Member of the college of Chest Physicians of India: Admitted as Member of the college of Chest Physicians of India, in Feb.1996
• Member of Mumbai Haematology and Medical Oncology Association
• Member of Mumbai Stem Cell Transplant Association
• Member as Transplant Physician of DKMS stem cell registry, Germany